Tıbbi Hizmetler ve Teknikleri Bölümü Koleksiyonu: Recent submissions
Now showing items 21-27 of 27
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Apoptotic, antioxidant and antiradical effects of majdine and isomajdine from Vinca herbacea Waldst. and kit
(2012)herbacea Waldst. and Kit were studied. For testing the possible apoptotic effects of majdine and isomajdine from V. herbacea, DNA fragmentation assay was conducted on the rat brain cortical tissue homogenates, in vitro. ... -
In vitro inhibition of a-carbonic anhydrase isozymes by some phenolic compounds
(2011)Carbonic anhydrase inhibitors (CAIs) are a class of pharmaceuticals used as antiglaucoma agents, diuret-ics, antiepileptics, in the management of mountain sickness, gastric and duodenal ulcers, neurological disorders or ... -
Antioxidant, antibacterial, and anticandidal activities of an aquatic plant: duckweed (Lemna minor L. Lemnaceae)
(2010)Abstract: Duckweed (Lemna minor L. Lemnaceae) is a widespread, free-floating aquatic macrophyte, a source of food for waterfowl and a shelter for small aquatic invertebrates. It grows quickly and reproduces faster than ... -
Antioxidant Activity of Bisbenzylisoquinoline Alkaloids from Stephania rotunda: Cepharanthine and fangchinoline
(2009-03-25)In the present study, we determined the antioxidant activity of cepharanthine and fangchinoline from Stephania rotunda by performing different in vitro antioxidant assays including 1,1-diphenyl-2-picryl hydrazyl free ... -
Rosmarinic acid: a potent carbonic anhydrase isoenzymes inhibitor
(2014-08-15)Rosmarinic acid is a water-soluble ester of ca eic acid and 3,4-dihydroxyphenyllactic acids, and is mainly found in plant species including Boraginaceae and Lamiaceae. In this research, we determined the inhibition property ... -
Novel Sulphamides and Sulphonamides Incorporating the Tetralin Scaffold as Carbonic Anhydrase and Acetylcholine Esterase Inhibitors
(2013-09-17)Reactions of amino, aminomethyl tetralins and benzyl alcohol with chlorosulphonyl isocyanate (CSI) afforded sulphamoyl carbamates. The sulphamoyl carbamates were converted to sulphamides by palladium-catalysed hydrogenolysis. ... -
(3,4-Dihydroxyphenyl)(2,3,4-trihydroxyphenyl)methanone and its derivatives as carbonic anhydrase isoenzymes inhibitors
(Journal of Enzyme Inhibition and Medicinal Chemistry, 2013-04)In this study, we have synthesised (3,4-dihydroxyphenyl)(2,3,4-trihydroxyphenyl)methanone and a series of its derivatives (5, 13–16) and tested the ability of these compounds to inhibit two metalloenzyme human carbonic ...
