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dc.contributor.authorSarikaya, Sevim B. Oezturk
dc.contributor.authorKaya, Afsin A.
dc.contributor.authorKaya, Elif Celenk
dc.contributor.authorSentuerk, Murat
dc.date.accessioned2021-11-09T19:43:06Z
dc.date.available2021-11-09T19:43:06Z
dc.date.issued2015
dc.identifier.issn0365-6233
dc.identifier.issn1521-4184
dc.identifier.urihttps://doi.org/10.1002/ardp.201400330
dc.identifier.urihttps://hdl.handle.net/20.500.12440/3549
dc.description.abstractThe antioxidant and radical scavenging activities of the synthesized compounds 3, 5, and 6 were determined by various in vitro assays such as 2,2-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid radical (ABTS(+)) scavenging, ferric ion (Fe3+) reducing power and ferrous ion (Fe2+) chelating activities. Moreover, these activities were compared to those of standard antioxidants such as butylated hydroxyanisole, butylated hydroxytoluene, and trolox. The results showed that the new compounds (3, 5, and 6) had potential antioxidant activity. Besides, inhibition of the two human cytosolic carbonic anhydrase (hCA, EC 4.2.1.1) isozymes I and II with some nitrobenzene compounds was investigated. Compounds 1-6 showed K-i values in the range of 4.88-193.4 mu M and 5.295-54.75 mu M for hCA I and hCA II, respectively.en_US
dc.description.sponsorshipGumushane University (BAP)Gumushane University [13.B0110.02.1]en_US
dc.description.sponsorshipThis study was financed by Gumushane University (BAP) (Project No: 13.B0110.02.1) for (A.A.K.). And the authors were indebted to their universities for financial support and using their laboratory equipments.en_US
dc.language.isoengen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.relation.ispartofArchiv Der Pharmazieen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntioxidant activityen_US
dc.subjectCarbonic anhydraseen_US
dc.subjectEnzyme inhibitoren_US
dc.subjectNitrobenzeneen_US
dc.titleSynthesis and Determination of Some Biological Activities of Novel 2,4-Dinitrophenyl Derivativesen_US
dc.typearticleen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.description.wospublicationidWOS:000350502100006en_US
dc.description.scopuspublicationid2-s2.0-84923833870en_US
dc.departmentGümüşhane Üniversitesien_US
dc.authoridSenturk, Murat / 0000-0001-5968-7511
dc.authoridKAYA, AFSIN AHMET / 0000-0003-2082-6478
dc.identifier.volume348en_US
dc.identifier.issue3en_US
dc.identifier.startpage214en_US
dc.identifier.doi10.1002/ardp.201400330
dc.identifier.endpage220en_US
dc.authorwosidKaya, Afsin Ahmet / AAD-9431-2019
dc.authorwosidSenturk, Murat / C-4491-2012
dc.authorscopusid39262128900
dc.authorscopusid25930389000
dc.authorscopusid36088399600
dc.authorscopusid23013520200
dc.description.pubmedpublicationidPubMed: 25644396en_US


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