Yazar "Topal, Fevzi" için PubMed İndeksli Yayınlar Koleksiyonu listeleme
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Acetylcholinesterase and carbonic anhydrase isoenzymes I and II inhibition profiles of taxifolin
Gocer, Hulya; Topal, Fevzi; Topal, Meryem; Kucuk, Murat; Teke, Dilek; Gulcin, Ilhami; Supuran, Claudiu T. (Taylor & Francis Ltd, 2016)Taxifolin, also known as dihydroquercetin, is a flavonoid commonly found in plants. Carbonic anhydrase (CA, EC 4.2.1.1) plays an important role in many critical physiological events including carbon dioxide (CO2)/bicarbonate ... -
Antioxidant activity of taxifolin: an activity-structure relationship
Topal, Fevzi; Nar, Meryem; Gocer, Hulya; Kalin, Pinar; Kocyigit, Umit M.; Gulcin, Ilhami; Alwasel, Saleh H. (Taylor & Francis Ltd, 2016)Taxifolin is a kind of flavanonol, whose biological ability. The objectives of this study were to investigate the antioxidants and antiradical activities of taxifolin by using different in vitro bioanalytical antioxidant ... -
Antioxidant, antiradical, and anticholinergic properties of cynarin purified from the Illyrian thistle (Onopordum illyricum L.)
Topal, Meryem; Gocer, Hulya; Topal, Fevzi; Kalin, Pinar; Kose, Leyla Polat; Gulcin, Ilhami; Alwasel, Saleh H. (Taylor & Francis Ltd, 2016)Cynarin is a derivative of hydroxycinnamic acid and it has biologically active functional groups constituent of some plants and food. We elucidated the antioxidant activity of cynarin by using different in vitro condition ... -
In vitro inhibition of alpha-carbonic anhydrase isozymes by some phenolic compounds
Sarikaya, Sevim Beyza Ozturk; Topal, Fevzi; Senturk, Murat; Gulcin, Ilhami; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2011)Carbonic anhydrase inhibitors (CAIs) are a class of pharmaceuticals used as antiglaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, gastric and duodenal ulcers, neurological disorders or ... -
Inhibition Profiles of Some Symmetric Sulfamides Derived from Phenethylamines on Human Carbonic Anhydrase I, and II Isoenzymes
Topal, Fevzi; Aksu, Kadir; Gulcin, Ilhami; Tumer, Ferhan; Goksu, Suleyman (Wiley-V C H Verlag Gmbh, 2021)In this work, the inhibitory effect of some symmetric sulfamides derived from phenethylamines were determined against human carbonic anhydrase (hCA) I, and II isoenzymes, and compared with standard compound acetazolamide. ... -
Inhibition profiles of Voriconazole against acetylcholinesterase, alpha-glycosidase, and human carbonic anhydrase I and II isoenzymes
Topal, Fevzi (Wiley, 2019)In this work, the inhibitory activity of Voriconazole was measured against some metabolic enzymes, including human carbonic anhydrase (hCA) I and II isoenzymes, acetylcholinesterase (AChE), and alpha-glycosidase; the results ... -
LC-HRMS Profiling and Antidiabetic, Anticholinergic, and Antioxidant Activities of Aerial Parts of Kinkor (Ferulago stellata)
Kiziltas, Hatice; Bingol, Zeynebe; Goren, Ahmet Ceyhan; Kose, Leyla Polat; Durmaz, Lokman; Topal, Fevzi; Gulcin, Ilhami (Mdpi, 2021)Kinkor (Ferulago stellata) is Turkish medicinal plant species and used in folk medicine against some diseases. As far as we know, the data are not available on the biological activities and chemical composition of this ... -
LC-HRMS Profiling and Phenolic Content, Cholinesterase, and Antioxidant Activities of Terminalia citrina
Ebubekir Özler; Fevzi Topal; Meryem Topal; Sevim Beyza Öztürk Sarıkaya (WILEY, 2023)Terminalia citrina (T. citrina) belongs to the Combretaceae family and is included in the class of medicinal plants in tropical countries such as Bangladesh, Myanmar, and India. The antioxidant activities of lyophilized ... -
Novel eugenol derivatives: Potent acetylcholinesterase and carbonic anhydrase inhibitors
Topal, Fevzi; Gulcin, Ilhami; Dastan, Arif; Guney, Murat (Elsevier Science Bv, 2017)Eugenol was used as starting material to obtain some phenolic compounds. The synthesis of these phenolic compounds was performed in a two-step procedure. The structures of the formed products (novel eugenol derivatives ... -
Oxidation of cyanobenzocycloheptatrienes: Synthesis, photooxygenation reaction and carbonic anhydrase isoenzymes inhibition properties of some new benzotropone derivatives
Guney, Murat; Coskun, Ahmet; Topal, Fevzi; Dastan, Arif; Gulcin, Ilhami; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2014)The oxidation of some cyanocycloheptatrienes with CrO3 and pyridine was investigated and a few new nitrile functionalised benzotropone derivatives were obtained. Photooxygenation reaction of these products was also studied. ... -
Synthesis and Carbonic Anhydrase Inhibitory Effects of Novel Sulfamides Derived from 1-Aminoindanes and Anilines
Akbaba, Yusuf; Bastem, Enes; Topal, Fevzi; Gulcin, Ilhami; Maras, Ahmet; Goksu, Suleyman (Wiley-V C H Verlag Gmbh, 2014)Three 1-aminoindanes, four anilines and BnOH or t-BuOH were reacted with chlorosulfonyl isocyanate to give sulfamoyl carbamates. Pd-C catalysed hydrogenolysis reactions of carbamates or deprotection of the Boc group of the ...