Yazar "Topal, Meryem" için WoS İndeksli Yayınlar Koleksiyonu listeleme
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9,10-Dibromo-N-aryl-9,10-dihydro-9,10-[3,4]epipyrroloanthracene-12,14-diones: Synthesis and Investigation of Their Effects on Carbonic Anhydrase Isozymes I, II, IX, and XII
Goksu, Haydar; Topal, Meryem; Keskin, Ali; Gultekin, Mehmet S.; Celik, Murat; Gulcin, Ilhami; Supuran, Claudiu T. (Wiley-V C H Verlag Gmbh, 2016)N-substituted maleimides were synthesized from maleic anhydride and primary amines. 1,4-Dibromodibenzo[e,h]bicyclo-[2,2,2]octane-2,3-dicarboximide derivatives (4a-f) were prepared by the [4+2] cycloaddition reaction of ... -
Acetylcholinesterase and carbonic anhydrase isoenzymes I and II inhibition profiles of taxifolin
Gocer, Hulya; Topal, Fevzi; Topal, Meryem; Kucuk, Murat; Teke, Dilek; Gulcin, Ilhami; Supuran, Claudiu T. (Taylor & Francis Ltd, 2016)Taxifolin, also known as dihydroquercetin, is a flavonoid commonly found in plants. Carbonic anhydrase (CA, EC 4.2.1.1) plays an important role in many critical physiological events including carbon dioxide (CO2)/bicarbonate ... -
Anticholinergic, antidiabetic and antioxidant activities of cinnamon (cinnamomum verum) bark extracts: polyphenol contents analysis by LC-MS/MS
Gulcin, Ilhami; Kaya, Ruya; Goren, Ahmet C.; Akincioglu, Hulya; Topal, Meryem; Bingol, Zeynebe; Alwasel, Saleh (Taylor & Francis Inc, 2019)Ethanolic (EEC) and aqueous (WEC) extracts of cinnamon (Cinnamomum verum) were evaluated for their antioxidant profiles by eight distinguished bioanalytical antioxidant methods. Their inhibitory effects were tested against ... -
Antidiabetic, anticholinergic and antioxidant activities of aerial parts of shaggy bindweed (Convulvulus betonicifolia Miller subsp.) - profiling of phenolic compounds by LC-HRMS
Bingol, Zeynebe; Kiziltas, Hatice; Goren, Ahmet C.; Kose, Leyla Polat; Topal, Meryem; Durmaz, Lokman; Gulcin, Ilhami (Elsevier Sci Ltd, 2021)In order to evaluate the antioxidant activity of evaporated ethanolic extract (EESB) and lyophilized water extract (WESB) of Shaggy bindweed (Convulvulus betonicifolia Mill. Subs), some putative antioxidant methods such ... -
Antioxidant, antiradical, and anticholinergic properties of cynarin purified from the Illyrian thistle (Onopordum illyricum L.)
Topal, Meryem; Gocer, Hulya; Topal, Fevzi; Kalin, Pinar; Kose, Leyla Polat; Gulcin, Ilhami; Alwasel, Saleh H. (Taylor & Francis Ltd, 2016)Cynarin is a derivative of hydroxycinnamic acid and it has biologically active functional groups constituent of some plants and food. We elucidated the antioxidant activity of cynarin by using different in vitro condition ... -
Determination of Angelica archangelica's Antioxidant Capacity and Mineral Content
Topal, Meryem; Ozturk Sarikaya, S. Beyza; Topal, Fevzi (Wiley-V C H Verlag Gmbh, 2021)The aim of this study was to determine the mineral contents by ICP-MS and the antioxidant capacity of Angelica archangelica plant, which is not well known in the literature. For this purpose, ethyl alcohol extracts of the ... -
Determination of the Antioxidant Capacity of Puerarin and Its Effect on Cholinesterases by in vitro and in silico Methods
İnan Ergün, Aslı; Topal, Meryem (John Wiley and Sons Inc, 2023)Puerarin, which was used as a natural isoflavone in this study, was obtained from the Kudzu plant. The inhibitory effect of puerarin on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes was investigated. ... -
The inhibition profile of sesamol against alpha-glycosidase and acetylcholinesterase enzymes
Topal, Meryem (Taylor & Francis Inc, 2019)Sesamol (1,3-benzodioxol-5-ol) is found in the oilseed product, sesame. In our study, the inhibitory effects of sesamol compound on acetylcholinesterase and alpha-glycosidase enzymes were evaluated. Another aim of this ... -
N-Acylsulfonamides strongly inhibit human carbonic anhydrase isoenzymes I and II
Yildirim, Alper; Atmaca, Ufuk; Keskin, Ali; Topal, Meryem; Celik, Murat; Gulcin, Ilhami; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2015)Sulfonamides represent a significant class of biologically active compounds that inhibit carbonic anhydrase (CA, EC.: 4.2.1.1) isoenzymes involved in different pathological and physiological events. Sulfonamide CA inhibitors ... -
Secondary Metabolites of Ethanol Extracts of Pinus sylvestris Cones from Eastern Anatolia and Their Antioxidant, Cholinesterase and alpha-Glucosidase Activities
Topal, Meryem (Acg Publications, 2020)Scots pine (Pinus sylvestris) is the most widely distributed tree species among pine species. Antiradical, antioxidant properties and inhibition properties on butyrylcholinesterase (BChE), acetylcholinesterase (AChE) and ... -
Synthesis of some natural sulphonamide derivatives as carbonic anhydrase inhibitors
Gokcen, Taner; Al, Melike; Topal, Meryem; Gulcin, Ilhami; Ozturk, Turan; Goren, Ahmet C. (Acg Publications, 2017)Carbonic anhydrase inhibitor; sulphonamides; p-hydroxybenzoic acid; 3,4,5-trihydroxybenzoic acid (gallic acid).Carbonic anhydrase inhibitors are both in clinical use as antiglaucoma, diuretics, antiepileptics and management ...