Browsing by Author "Duzgun, Azer Ozad"
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Antibiotic induced biofilm formation of novel multidrug resistant Acinetobacter baumannii ST2121 clone
Cimen, Muberra; Duzgun, Azer Ozad (Akademiai Kiado Zrt, 2021)The aim of this study was to identify antimicrobial resistance and virulence factor genes exhibited by multidrug resistant (MDR) Acinetobacter baumannii, to analyze biofilm formation and to investigate clonal subtypes of ... -
BIOLOGICAL ACTIVITIES AND PHYTOCHEMICAL SCREENING OF ETHANOL EXTRACTS FROM ADONIS PARYADRICA (RANUNCULACEAE)
Ucuncu, Osman; Baltaci, Cemalettin; Akar, Zeynep; Duzgun, Azer Ozad; Cuce, Mustafa; Kandemir, Ali (Soc Stiinte Farmaceutice Romania, 2020)In this study, secondary metabolite profiles of flower, leaf and root of Adonis paryadrica ethanolic extracts were performed by using a newly developed and validated LC-MS/MS method. For this purpose, the LC-MS/MS system ... -
Characterization of novel VIM carbapenemase, VIM-38, and first detection of GES-5 carbapenem-hydrolyzing beta-lactamases in Pseudomonas aeruginosa in Turkey
Iraz, Meryem; Duzgun, Azer Ozad; Cicek, Aysegul Copur; Bonnin, Remy A.; Ceylan, Aysenur; Saral, Aysegul; Sandalli, Cemal (Elsevier Science Inc, 2014)Pseudomonas aeruginosa isolates were collected form a Turkish hospital. Antimicrobial susceptibility was performed using the Vitek 2 Compact system, and 24 isolates were categorized as multidrug resistant (n = 18), ... -
Determination of antibiotic resistance genes and virulence factors in Escherichia coli isolated from Turkish patients with urinary tract infection
Duzgun, Azer Ozad; Okumus, Funda; Saral, Aysegul; Cicek, Aysegul Copur; Cinemre, Sedanur (Soc Brasileira Medicina Tropical, 2019)Introduction: Escherichia coli ranks among the most common sources of urinary tract infections (UTI). Methods: Between November 2015 and August 2016, 90 isolates of E coli were isolated from patients at Rize Education and ... -
Distribution of beta-Lactamase Genes Among Carbapenem-Resistant Klebsiella pneumoniae Strains Isolated From Patients in Turkey
Iraz, Meryem; Duzgun, Azer Ozad; Sandalli, Cemal; Doymaz, Mehmet Ziya; Akkoyunlu, Yasemin; Saral, Aysegul; Cicek, Aysegul Copur (Korean Soc Laboratory Medicine, 2015)Background: The emergence of carbapenem-resistant Klebsiella pneumoniae poses a serious problem to antibiotic management. We investigated the beta-lactamases in a group of carbapenem-resistant K. pneumoniae clinical isolates ... -
EFFECT OF AMINO ACID SUBSTITUTION IN NEW DELHI METALLO-beta-LACTAMASE ON CARBAPENEM SUSCEPTIBILITY
Duzgun, Azer Ozad (Akademiai Kiado Zrt, 2018)The aim of this work was investigation of clinically important amino acid substitutions of NDM-1 variants. A bla(NDM-1) gene was cloned into expression vector pET100/D-TOPO. The sequence of NDM-1 variants with substituted ... -
From Turkey: First Report of KPC-3-and CTX-M-27-Producing Multidrug-Resistant Klebsiella pneumoniae ST147 Clone Carrying OmpK36 and Ompk37 Porin Mutations
Duzgun, Azer Ozad (Mary Ann Liebert, Inc, 2021)Aim: The aim of this study was to identify antimicrobial resistance genes, virulence factor genes, and porin loss or mutations exhibited by the multidrug-resistant Klebsiella pneumoniae strain. Materials and Methods: ... -
Kinetic characterization of GES-22 beta-lactamase harboring the M169L clinical mutation
Saral, Aysegul; Leonard, David A.; Duzgun, Azer Ozad; Cicek, Aysegul Copur; June, Cynthia M.; Sandalli, Cemal (Japan Antibiotics Research Assoc, 2016)The class A p-lactamase GES-22 has been identified in Acinetobacter baumannii isolates in Turkey, and subsequently shown to differ from GES-11 by a single substitution (M169L). Because M169 is part of the omega loop, a ... -
NEXT-GENERATION SEQUENCING OF PLASMID CARRYING bla(OXA-48) IN KLEBSIELLA PNEUMONIAE FROM TURKEY
Duzgun, Azer Ozad; Saral, Aysegul (Akademiai Kiado Zrt, 2019)A carbapenem-resistant Klebsiella pneumoniae strain was isolated in Turkey in 2012 and bla(NDM-1) and bla(OXA-48) genes were observed in this strain. The aim of this study was to investigate transferability of plasmid ...