Browsing by Author "Deger, Orhan"
Now showing items 1-14 of 14
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Antioxidant Properties and Protective Effect of Turkish Propolis on t-BHP-Induced Oxidative Stress in Foreskin Fibroblast Cells
Misir, Sema; Aliyazicioglu, Yuksel; Demir, Selim; Turan, Ibrahim; Yaman, Serap Ozer; Deger, Orhan (Assoc Pharmaceutical Teachers India, 2018)Objective: Propolis is an important bee product, rich in polyphenolic compounds. It has antitumoral, antioxidant, antimutagenic, and other useful activities. Biological activities of propolis are generally attributed to ... -
Antiproliferative and apoptotic effect of Morus nigra extract on human prostate cancer cells
Turan, Ibrahim; Demir, Selim; Kilinc, Kagan; Burnaz, Nesibe Arslan; Yaman, Serap Ozer; Akbulut, Kubra; Deger, Orhan (Elsevier Science Bv, 2017)Background: Morus nigra L. belongs to the family Moraceae and is frequently used in traditional medicine. Numerous studies have investigated the antiproliferative effects of various extracts of different Morus species, but ... -
Antiproliferative and proapoptotic activity of Turkish propolis on human lung cancer cell line
Demir, Selim; Aliyazicioglu, Yuksel; Turan, Ibrahim; Misir, Sema; Mentese, Ahmet; Yaman, Serap Ozer; Deger, Orhan (Routledge Journals, Taylor & Francis Ltd, 2016)Cancer is a heterogeneous disease, two of whose characteristic features are uncontrollable cell proliferation and insufficient apoptosis. Various studies have investigated the antiproliferative effects of propolis, a natural ... -
Cytotoxic effect of Rosa canina extract on human colon cancer cells through repression of telomerase expression
Turan, Ibrahim; Demir, Selim; Kilinc, Kagan; Yaman, Serap Ozer; Misir, Sema; Kara, Hanife; Deger, Orhan (Elsevier Science Bv, 2018)Rosa canina is a member of the genus Rosa that has long been used for medical objectives. Several studies have reported cytotoxic effects of different Rosa species, but there has been only limited investigation of the ... -
Cytotoxic Effect of Turkish Propolis on Liver, Colon, Breast, Cervix and Prostate Cancer Cell Lines
Turan, Ibrahim; Demir, Selim; Misir, Sema; Kilinc, Kagan; Mentese, Ahmet; Aliyazicioglu, Yuksel; Deger, Orhan (Pharmacotherapy Group, 2015)Purpose: To investigate the total polyphenolic and flavonoid contents, antioxidant power and cytotoxic activity of ethanol extracts of Turkish propolis (EEP). Methods: The total polyphenolic and flavonoid contents of EEP ... -
Dimethyl Sulfoxide Extract of Dianthus carmelitarum Induces S Phase Arrest and Apoptosis in Human Colon Cancer Cells
Turan, Ibrahim; Demir, Selim; Aliyazicioglu, Rezzan; Kilinc, Kagan; Yaman, Serap Ozer; Cakiroglu, Kubra Akbulut; Deger, Orhan (Routledge Journals, Taylor & Francis Ltd, 2019)Although several studies have investigated the cytotoxic effects of different Dianthus species, there has been only limited research into the cytotoxic effect of Dianthus carmelitarum. The purpose of this research was to ... -
Effect of Turkish pollen and propolis extracts on caspase-3 activity in myeloid cancer cell lines
Ucar, Meltem; Deger, Orhan; Gerigelmez, Asuman Yigit; Cengiz, Sevil; Barlak, Yasam; Ovali, Ercument (Pharmacotherapy Group, 2016)Purpose: To investigate the apoptosis-inducing capacity of dimethyl sulfoxide (DMSO) extracts of bee pollen and propolis in HL-60 Myeloid Cancer Cell Lines. Methods: DMSO extracts of pollen and propolis were incubated ... -
Effect of Turkish propolis extracts on proteome of prostate cancer cell line
Barlak, Yasam; Deger, Orhan; Colak, Meltem; Karatayli, Senem Ceren; Bozdayi, Abdurrahman Mithat; Yucesan, Fulya (Bmc, 2011)Background: Propolis is a natural, resinous hive product that has several pharmacological activities. Its composition varies depending on the vegetation, climate, season and environmental conditions of the area from where ... -
Evaluation of the radioprotective effect of Turkish propolis on foreskin fibroblast cells
Yalcin, Can Ozgur; Aliyazicioglu, Yuksel; Demir, Selim; Turan, Ibrahim; Bahat, Zumrut; Misir, Sema; Deger, Orhan (Wolters Kluwer Medknow Publications, 2016)Aim of Study: Propolis is a resinous bee product, rich of polyphenolic compounds and flavonoids. It is known that in different geographic zones its chemical composition varies due to the different plant sources. Many ... -
Morus Rubra Extract Induces Cell Cycle Arrest and Apoptosis in Human Colon Cancer Cells Through Endoplasmic Reticulum Stress and Telomerase
Demir, Selim; Turan, Ibrahim; Aliyazicioglu, Yuksel; Kilinc, Kagan; Yaman, Serap Ozer; Demir, Elif Ayazoglu; Deger, Orhan (Routledge Journals, Taylor & Francis Ltd, 2017)Many studies have reported cytotoxic effects of different Morus species, but there have been only limited studies on the cytotoxic effect of Morus rubra. The aims of this study were to evaluate the cytotoxic effect of ... -
Morus rubra Extract Induces G(1) Cell Cycle Arrest and Apoptosis in Human Lung and Prostate Cancer Cells
Turan, Ibrahim; Demir, Selim; Kilinc, Kagan; Aliyazicioglu, Yuksel; Alver, Ahmet; Misir, Sema; Deger, Orhan (Assoc Pharmaceutical Teachers India, 2017)Objective: Cancer is one of the most deadly types of disease and evasion from apoptosis and unstoppable cell proliferation are accepted as its distinctive features. Many studies have evaluated the cytotoxic effect of ... -
Morus rubra Extract Induces G1 Cell Cycle Arrest and Apoptosis in Human Lung and Prostate Cancer Cells
Turan, Ibrahim; Demir, Selim; Kilinc, Kagan; Aliyazıcıoglu, Yuksel; Alver, Ahmet; Misir, Sema; Özer Yaman, Serap; Akbulut Cakiroglu, Kubra; Mentese, Ahmet; Deger, Orhan (Indian Journal of Pharmaceutical Education and Research, 2017-01)[Abstract Not Available] -
The Relationship Between the Peroxisome Proliferator-Activated Receptor Gamma 2 Gene Polymorphism, Lipids and Adipokines in Patients with Major Depression
Aliyazicioglu, Rezzan; Deger, Orhan; Kural, Birgul Vanizor; Hocaoglu, Cicek; Colak, Meltem; Yucesan, Fulya Balaban (Ortadogu Ad Pres & Publ Co, 2011)Objective: Peroxisome proliferator-activated receptor gamma (PPAR gamma), lipids, lipoproteins, and adipokines have recently been shown to be associated with psychiatric diseases. Our major aim is to investigate the ... -
Sequence Variant in the LPIN1 gene in Patients with Metabolic Syndrome
Kural, Birgul Vanizor; Deger, Orhan; Erem, Cihangir; Yucesan, Fulya Balaban; Barlak, Yasam; Turan, Ibrahim; Aliyazicioglu, Rezzan (Walter De Gruyter Gmbh, 2013)Objective: Metabolic syndrome (MetS) is a complex disease characterized by insulin resistance, abdominal obesity, hyperglycemia, hypertension, hypertriglyceridemia and low HDL-cholesterol level. The aim of the study was ...