Browsing by Author "Aliyazicioglu, Yuksel"
Now showing items 1-17 of 17
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Antioxidant Properties and Protective Effect of Turkish Propolis on t-BHP-Induced Oxidative Stress in Foreskin Fibroblast Cells
Misir, Sema; Aliyazicioglu, Yuksel; Demir, Selim; Turan, Ibrahim; Yaman, Serap Ozer; Deger, Orhan (Assoc Pharmaceutical Teachers India, 2018)Objective: Propolis is an important bee product, rich in polyphenolic compounds. It has antitumoral, antioxidant, antimutagenic, and other useful activities. Biological activities of propolis are generally attributed to ... -
Antiproliferative and proapoptotic activity of Turkish propolis on human lung cancer cell line
Demir, Selim; Aliyazicioglu, Yuksel; Turan, Ibrahim; Misir, Sema; Mentese, Ahmet; Yaman, Serap Ozer; Deger, Orhan (Routledge Journals, Taylor & Francis Ltd, 2016)Cancer is a heterogeneous disease, two of whose characteristic features are uncontrollable cell proliferation and insufficient apoptosis. Various studies have investigated the antiproliferative effects of propolis, a natural ... -
Cytotoxic Effect of Turkish Propolis on Liver, Colon, Breast, Cervix and Prostate Cancer Cell Lines
Turan, Ibrahim; Demir, Selim; Misir, Sema; Kilinc, Kagan; Mentese, Ahmet; Aliyazicioglu, Yuksel; Deger, Orhan (Pharmacotherapy Group, 2015)Purpose: To investigate the total polyphenolic and flavonoid contents, antioxidant power and cytotoxic activity of ethanol extracts of Turkish propolis (EEP). Methods: The total polyphenolic and flavonoid contents of EEP ... -
Dimethyl Sulfoxide Extract of iDianthus carmelitarum/i Induces S Phase Arrest and Apoptosis in Human Colon Cancer Cells
Turan, İbrahim; Demir, Selim; Aliyazicioglu, Rezzan; Kilinc, Kagan; Ozer Yaman, Serap; Akbulut Cakiroglu, Kubra; Kanbolat, Seyda; Ayazoglu Demir, Elif; Mentese, Ahmet; Aliyazicioglu, Yuksel; Değer, Orhan (Nutrition and Cancer / Taylor & Francis Online, 2019-04)[Abstract Not Available] -
The effect of prenatal exposure to 900-MHz electromagnetic field on the 21-old-day rat testicle
Hanci, Hatice; Odaci, Ersan; Kaya, Haydar; Aliyazicioglu, Yuksel; Turan, Ibrahim; Demir, Selim; Colakoglu, Serdar (Pergamon-Elsevier Science Ltd, 2013)The aim of this study was to investigate the effect of exposure to a 900-MHz electromagnetic field (EMF) in the prenatal term on the 21-old-day rat testicle. Pregnant rats were divided into control (CG) and EMF (EMFG) ... -
Effect of Turkish Propolis on miRNA Expression, Cell Cycle, and Apoptosis in Human Breast Cancer (MCF-7) Cells
Misir, Sema; Aliyazicioglu, Yuksel; Demir, Selim; Turan, Ibrahim; Hepokur, Ceylan (Routledge Journals, Taylor & Francis Ltd, 2020)Enriched in flavonoid compounds, phenol acids, and terpene derivatives, propolis has been shown to regulate apoptosis signaling pathways and alter the expression of microRNAs (miRNAs). In the present study, it has been ... -
Evaluation of the radioprotective effect of Turkish propolis on foreskin fibroblast cells
Yalcin, Can Ozgur; Aliyazicioglu, Yuksel; Demir, Selim; Turan, Ibrahim; Bahat, Zumrut; Misir, Sema; Deger, Orhan (Wolters Kluwer Medknow Publications, 2016)Aim of Study: Propolis is a resinous bee product, rich of polyphenolic compounds and flavonoids. It is known that in different geographic zones its chemical composition varies due to the different plant sources. Many ... -
An Investigation of the Antiproliferative Effect of Rhododendron luteum Extract on Cervical Cancer (HeLa) Cells via Nrf2 Signaling Pathway
Turan, Ibrahim; Demir, Selim; Yaman, Serap Ozer; Canbolat, Deniz; Mentese, Ahmet; Aliyazicioglu, Yuksel (Routledge Journals, Taylor & Francis Ltd, 2021)The aim of the present study was to investigate the role of Rhododendron luteum extract (RLE) in the induction of Nrf2-related oxidative stress and endoplasmic reticulum (ER) stress in human cervical cancer (HeLa) cells. ... -
Morus Rubra Extract Induces Cell Cycle Arrest and Apoptosis in Human Colon Cancer Cells Through Endoplasmic Reticulum Stress and Telomerase
Demir, Selim; Turan, Ibrahim; Aliyazicioglu, Yuksel; Kilinc, Kagan; Yaman, Serap Ozer; Demir, Elif Ayazoglu; Deger, Orhan (Routledge Journals, Taylor & Francis Ltd, 2017)Many studies have reported cytotoxic effects of different Morus species, but there have been only limited studies on the cytotoxic effect of Morus rubra. The aims of this study were to evaluate the cytotoxic effect of ... -
Morus rubra Extract Induces G(1) Cell Cycle Arrest and Apoptosis in Human Lung and Prostate Cancer Cells
Turan, Ibrahim; Demir, Selim; Kilinc, Kagan; Aliyazicioglu, Yuksel; Alver, Ahmet; Misir, Sema; Deger, Orhan (Assoc Pharmaceutical Teachers India, 2017)Objective: Cancer is one of the most deadly types of disease and evasion from apoptosis and unstoppable cell proliferation are accepted as its distinctive features. Many studies have evaluated the cytotoxic effect of ... -
Phenolic Characterisation and Antioxidant Activity of Primula vulgaris and Its Antigenotoxic Effect on Fibroblast Cells
Ozkan, Mehtap Tugce; Aliyazicioglu, Rezzan; Demir, Selim; Misir, Sema; Turan, Ibrahim; Yildirmis, Sermet; Aliyazicioglu, Yuksel (Kowsar Publ, 2017)Background: Primula vulgaris has been used in traditional treatment, and its biological functions are attributed to its polyphenolics content. Objectives: The aim of this study was to determine the phenolics composition ... -
Phytochemical Analysis of Dorycnium pentaphyllum and Its Antiproliferative Effect on Cervix Cancer Cells
Aliyazicioglu, Yuksel; Demir, Selim; Yaman, Scrap Ozer; Sener, Sila Ozlem; Demir, Elif Ayazoglu; Aliyazicioglu, Rezzan; Turan, Ibrahim (Kahramanmaras Sutcu Imam Univ Rektorlugu, 2019)The purpose of this study was to investigate the phytochemical analysis of D. pentaphyllum and its cytotoxic activity on human cervical cancer (HeLa) cells with possible mechanisms. Total phenolic contents (TPC) and ... -
Positive correlation between insulin resistance and iron overload-induced oxidative stress in patients with fanconi anemia (FA)- and non-FA-related bone marrow failure: The results of a multicenter study
Erduran, Erol; Bahadir, Aysenur; Albayrak, Davut; Aliyazicioglu, Yuksel; Buyukavci, Mustafa; Turan, Ibrahim (Taylor & Francis Inc, 2016)This study investigated the relationship between DNA, protein, and lipid oxidations and insulin resistance in patients with Fanconi anemia (FA)- and non-FA-related bone marrow failure. Sixteen patients with FA, 7 non-FA-related ... -
PREVENTIVE AND PROTECTIVE EFFECTS OF TURKISH PROPOLIS ON H2O2-INDUCED DNA DAMAGE IN FORESKIN FIBROBLAST CELL LINES
Aliyazicioglu, Yuksel; Demir, S.; Turan, I.; Cakiroglu, Tugba Nigar; Akalin, I.; Deger, O.; Bedir, A. (Akademiai Kiado Zrt, 2011)The aim of the present study was to evaluate the potential of Turkish propolis extracts if they prevent or protect foreskin fibroblast cells against hydrogen peroxide (H2O2)-induced oxidative DNA damage. Hydrogen peroxide ... -
Primula vulgaris extract induces cell cycle arrest and apoptosis in human cervix cancer cells
Demir, Selim; Turan, Ibrahim; Aliyazicioglu, Rezzan; Yaman, Serap Ozer; Aliyazicioglu, Yuksel (Elsevier Science Bv, 2018)Primula vulgaris belongs to the genus Primula, members of which are frequently used in folk medicine. Various studies have investigated the cytotoxic effect of different Primula species, but there have been limited studies ... -
Rosa canina Extract has Antiproliferative and Proapoptotic Effects on Human Lung and Prostate Cancer Cells
Kilinc, Kagan; Demir, Selim; Turan, Ibrahim; Mentese, Ahmet; Orem, Asim; Sonmez, Mehmet; Aliyazicioglu, Yuksel (Routledge Journals, Taylor & Francis Ltd, 2020)Although several studies have investigated the cytotoxic effects of different Rosa species, there has been only limited research into the cytotoxic effect of Rosa canina. The purpose of this research was to evaluate the ... -
Selective cytotoxic effect of Rhododendron luteum extract on human colon and liver cancer cells
Demir, Selim; Turan, Ibrahim; Aliyazicioglu, Yuksel (Zerbinis Medical Publ, 2016)Purpose: The genus Rhododendron is distributed entirely in the world with the exception of South and Central America and Africa, growing in a large diversity of climatic conditions. This genus is a rich source of phenolic ...