ORCID "0000-0002-2443-2372" için listeleme
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Design and Synthesis of Pyrazole Carboxamide Derivatives as Selective Cholinesterase and Carbonic Anhydrase Inhibitors: Molecular Docking and Biological Evaluation
Mustafa Durgun; Suleyman Akocak; Nebih Lolak; Fevzi Topal; Ümit Muhammet Koçyiğit; Cüneyt Türkeş; Mesut Işık; Şükrü Beydemir (WILEY, 2023)The present study focused on the synthesis and characterization of novel pyrazole carboxamide derivatives (SA1-12). The inhibitory effect of the compounds on cholinesterases (ChEs; AChE and BChE) and carbonic anhydrases ... -
Novel asymmetric biscarbothioamides as Alzheimer's disease associated cholinesterase inhibitors: synthesis, biological activity, and molecular docking studies
Muǧlu, Halit; Yakan, Hasan; Erdoğan, Musa; Topal, Fevzi; Topal, Meryem (Royal Society of Chemistry, 3 June 202)Exploring novel frameworks for treating Alzheimer's disease is an ambitious objective. In this particular context, a range of asymmetric biscarbothioamide derivatives (3a-l) with varying substitutions have been meticulously ...