Yazar "Topal, Fevzi" için listeleme
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Acetylcholinesterase and carbonic anhydrase isoenzymes I and II inhibition profiles of taxifolin
Gocer, Hulya; Topal, Fevzi; Topal, Meryem; Kucuk, Murat; Teke, Dilek; Gulcin, Ilhami; Supuran, Claudiu T. (Taylor & Francis Ltd, 2016)Taxifolin, also known as dihydroquercetin, is a flavonoid commonly found in plants. Carbonic anhydrase (CA, EC 4.2.1.1) plays an important role in many critical physiological events including carbon dioxide (CO2)/bicarbonate ... -
Anticholinergic and antidiabetic effects of isoeugenol from clove (Eugenia caryophylata) oil
Topal, Fevzi (Taylor & Francis Inc, 2019)Isoeugenol (2-methoxy-4-(prop-1-en-1-yl)phenol), a component of from clove (Eugenia caryophylata) oil, is a starting material for both the biotechnological and synthetic production of vanillin and vanillic acid. In this ... -
Antidiabetic Potential: Effect of Resorcinol on ?-Glycosidase and ?-Amylase Enzymes
Topal, Fevzi (2018)The vast majority of the carbohydrates in the biomolecule class are formed by photosynthesis using sunlight. One of the important enzymes in this class is ?-glycosidase. This enzyme converts complex carbohydrates to ... -
Antioxidant Activity of Bisbenzylisoquinoline Alkaloids from Stephania rotunda: Cepharanthine and fangchinoline
Topal, Fevzi; Gülçin, İlhami; Elias, Riad; Gepdiremen, Akçahan; Chea, Aun (2009-03-25)In the present study, we determined the antioxidant activity of cepharanthine and fangchinoline from Stephania rotunda by performing different in vitro antioxidant assays including 1,1-diphenyl-2-picryl hydrazyl free ... -
Antioxidant activity of taxifolin: an activity-structure relationship
Topal, Fevzi; Nar, Meryem; Gocer, Hulya; Kalin, Pinar; Kocyigit, Umit M.; Gulcin, Ilhami; Alwasel, Saleh H. (Taylor & Francis Ltd, 2016)Taxifolin is a kind of flavanonol, whose biological ability. The objectives of this study were to investigate the antioxidants and antiradical activities of taxifolin by using different in vitro bioanalytical antioxidant ... -
Antioxidant, antibacterial, and anticandidal activities of an aquatic plant: duckweed (Lemna minor L. Lemnaceae)
Abstract: Duckweed (Lemna minor L. Lemnaceae) is a widespread, free-floating aquatic macrophyte, a source of food for waterfowl and a shelter for small aquatic invertebrates. It grows quickly and reproduces faster than ... -
Antioxidant, antiradical, and anticholinergic properties of cynarin purified from the Illyrian thistle (Onopordum illyricum L.)
Topal, Meryem; Gocer, Hulya; Topal, Fevzi; Kalin, Pinar; Kose, Leyla Polat; Gulcin, Ilhami; Alwasel, Saleh H. (Taylor & Francis Ltd, 2016)Cynarin is a derivative of hydroxycinnamic acid and it has biologically active functional groups constituent of some plants and food. We elucidated the antioxidant activity of cynarin by using different in vitro condition ... -
Apoptotic, antioxidant and antiradical effects of majdine and isomajdine from Vinca herbacea Waldst. and kit
Topal, Fevzi; Gülçin, İlhami; Beydemir, Şükrü; Gagua, Natia; Bakuridze, Aliko; Bayram, Recep; Gepdiremen, Akçahan (2012)herbacea Waldst. and Kit were studied. For testing the possible apoptotic effects of majdine and isomajdine from V. herbacea, DNA fragmentation assay was conducted on the rat brain cortical tissue homogenates, in vitro. ... -
Determination of Angelica archangelica's Antioxidant Capacity and Mineral Content
Topal, Meryem; Ozturk Sarikaya, S. Beyza; Topal, Fevzi (Wiley-V C H Verlag Gmbh, 2021)The aim of this study was to determine the mineral contents by ICP-MS and the antioxidant capacity of Angelica archangelica plant, which is not well known in the literature. For this purpose, ethyl alcohol extracts of the ... -
Determination of Antioxidant Capacity of 2,6-Quinolinediol
Topal, Fevzi (2019)The compounds of the quinolone group have been widely used in the alive metabolism, paint and pharmaceutical industry. Therefore, various quinoline derivatives are synthesized and synthesis methods are developed. The ... -
Gümüşhane'de farklı çevrelerde yetiştirilmiş bazı kışlık ekmeklik buğday genotiplerinin antioksidan kapasitelerinin belirlenmesi
İktü, Adem (Gümüşhane Üniversitesi, 2020)Bu çalışmada, Gümüşhane koşullarında farklı yetiştirme mevsimlerinde, organik ve konvansiyonel koşullarda yetiştirilmiş olan bazı ekmeklik buğday genotiplerinin kepek ve un fraksiyonlarının antioksidan aktivitelerinin ... -
In vitro inhibition of a-carbonic anhydrase isozymes by some phenolic compounds
Topal, Fevzi (2011)Carbonic anhydrase inhibitors (CAIs) are a class of pharmaceuticals used as antiglaucoma agents, diuret-ics, antiepileptics, in the management of mountain sickness, gastric and duodenal ulcers, neurological disorders or ... -
In vitro inhibition of alpha-carbonic anhydrase isozymes by some phenolic compounds
Sarikaya, Sevim Beyza Ozturk; Topal, Fevzi; Senturk, Murat; Gulcin, Ilhami; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2011)Carbonic anhydrase inhibitors (CAIs) are a class of pharmaceuticals used as antiglaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, gastric and duodenal ulcers, neurological disorders or ... -
Inhibition Profiles of Some Symmetric Sulfamides Derived from Phenethylamines on Human Carbonic Anhydrase I, and II Isoenzymes
Topal, Fevzi; Aksu, Kadir; Gulcin, Ilhami; Tumer, Ferhan; Goksu, Suleyman (Wiley-V C H Verlag Gmbh, 2021)In this work, the inhibitory effect of some symmetric sulfamides derived from phenethylamines were determined against human carbonic anhydrase (hCA) I, and II isoenzymes, and compared with standard compound acetazolamide. ... -
Inhibition profiles of Voriconazole against acetylcholinesterase, alpha-glycosidase, and human carbonic anhydrase I and II isoenzymes
Topal, Fevzi (Wiley, 2019)In this work, the inhibitory activity of Voriconazole was measured against some metabolic enzymes, including human carbonic anhydrase (hCA) I and II isoenzymes, acetylcholinesterase (AChE), and alpha-glycosidase; the results ... -
LC-HRMS Profiling and Antidiabetic, Anticholinergic, and Antioxidant Activities of Aerial Parts of Kinkor (Ferulago stellata)
Kiziltas, Hatice; Bingol, Zeynebe; Goren, Ahmet Ceyhan; Kose, Leyla Polat; Durmaz, Lokman; Topal, Fevzi; Gulcin, Ilhami (Mdpi, 2021)Kinkor (Ferulago stellata) is Turkish medicinal plant species and used in folk medicine against some diseases. As far as we know, the data are not available on the biological activities and chemical composition of this ... -
LC-HRMS Profiling and Phenolic Content, Cholinesterase, and Antioxidant Activities of Terminalia citrina
Ebubekir Özler; Fevzi Topal; Meryem Topal; Sevim Beyza Öztürk Sarıkaya (WILEY, 2023)Terminalia citrina (T. citrina) belongs to the Combretaceae family and is included in the class of medicinal plants in tropical countries such as Bangladesh, Myanmar, and India. The antioxidant activities of lyophilized ... -
Novel asymmetric biscarbothioamides as Alzheimer's disease associated cholinesterase inhibitors: synthesis, biological activity, and molecular docking studies
Muǧlu, Halit; Yakan, Hasan; Erdoğan, Musa; Topal, Fevzi; Topal, Meryem (Royal Society of Chemistry, 3 June 202)Exploring novel frameworks for treating Alzheimer's disease is an ambitious objective. In this particular context, a range of asymmetric biscarbothioamide derivatives (3a-l) with varying substitutions have been meticulously ... -
Novel eugenol derivatives: Potent acetylcholinesterase and carbonic anhydrase inhibitors
Topal, Fevzi; Gulcin, Ilhami; Dastan, Arif; Guney, Murat (Elsevier Science Bv, 2017)Eugenol was used as starting material to obtain some phenolic compounds. The synthesis of these phenolic compounds was performed in a two-step procedure. The structures of the formed products (novel eugenol derivatives ... -
Oxidation of cyanobenzocycloheptatrienes: Synthesis, photooxygenation reaction and carbonic anhydrase isoenzymes inhibition properties of some new benzotropone derivatives
Guney, Murat; Coskun, Ahmet; Topal, Fevzi; Dastan, Arif; Gulcin, Ilhami; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2014)The oxidation of some cyanocycloheptatrienes with CrO3 and pyridine was investigated and a few new nitrile functionalised benzotropone derivatives were obtained. Photooxygenation reaction of these products was also studied. ...
