Yazar "Supuran, Claudiu T." için listeleme
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9,10-Dibromo-N-aryl-9,10-dihydro-9,10-[3,4]epipyrroloanthracene-12,14-diones: Synthesis and Investigation of Their Effects on Carbonic Anhydrase Isozymes I, II, IX, and XII
Goksu, Haydar; Topal, Meryem; Keskin, Ali; Gultekin, Mehmet S.; Celik, Murat; Gulcin, Ilhami; Supuran, Claudiu T. (Wiley-V C H Verlag Gmbh, 2016)N-substituted maleimides were synthesized from maleic anhydride and primary amines. 1,4-Dibromodibenzo[e,h]bicyclo-[2,2,2]octane-2,3-dicarboximide derivatives (4a-f) were prepared by the [4+2] cycloaddition reaction of ... -
Acetylcholinesterase and carbonic anhydrase isoenzymes I and II inhibition profiles of taxifolin
Gocer, Hulya; Topal, Fevzi; Topal, Meryem; Kucuk, Murat; Teke, Dilek; Gulcin, Ilhami; Supuran, Claudiu T. (Taylor & Francis Ltd, 2016)Taxifolin, also known as dihydroquercetin, is a flavonoid commonly found in plants. Carbonic anhydrase (CA, EC 4.2.1.1) plays an important role in many critical physiological events including carbon dioxide (CO2)/bicarbonate ... -
In vitro inhibition of alpha-carbonic anhydrase isozymes by some phenolic compounds
Sarikaya, Sevim Beyza Ozturk; Topal, Fevzi; Senturk, Murat; Gulcin, Ilhami; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2011)Carbonic anhydrase inhibitors (CAIs) are a class of pharmaceuticals used as antiglaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, gastric and duodenal ulcers, neurological disorders or ... -
Investigation of the inhibitory properties of some phenolic standards and bee products against human carbonic anhydrase I and II
Aygul, Imdat; Karahalil, Fatma Yaylaci; Supuran, Claudiu T. (Taylor & Francis Ltd, 2016)Polyphenols are important secondary products of plants with the potential to inhibit carbonic anhydrases. The aim of this study was to investigate the inhibition effects of various phenolic standards, honey, propolis, and ... -
N-Acylsulfonamides strongly inhibit human carbonic anhydrase isoenzymes I and II
Yildirim, Alper; Atmaca, Ufuk; Keskin, Ali; Topal, Meryem; Celik, Murat; Gulcin, Ilhami; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2015)Sulfonamides represent a significant class of biologically active compounds that inhibit carbonic anhydrase (CA, EC.: 4.2.1.1) isoenzymes involved in different pathological and physiological events. Sulfonamide CA inhibitors ... -
Oxidation of cyanobenzocycloheptatrienes: Synthesis, photooxygenation reaction and carbonic anhydrase isoenzymes inhibition properties of some new benzotropone derivatives
Guney, Murat; Coskun, Ahmet; Topal, Fevzi; Dastan, Arif; Gulcin, Ilhami; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2014)The oxidation of some cyanocycloheptatrienes with CrO3 and pyridine was investigated and a few new nitrile functionalised benzotropone derivatives were obtained. Photooxygenation reaction of these products was also studied. ...
