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Design and Synthesis of Pyrazole Carboxamide Derivatives as Selective Cholinesterase and Carbonic Anhydrase Inhibitors: Molecular Docking and Biological Evaluation
Mustafa Durgun; Suleyman Akocak; Nebih Lolak; Fevzi Topal; Ümit Muhammet Koçyiğit; Cüneyt Türkeş; Mesut Işık; Şükrü Beydemir (WILEY, 2023)The present study focused on the synthesis and characterization of novel pyrazole carboxamide derivatives (SA1-12). The inhibitory effect of the compounds on cholinesterases (ChEs; AChE and BChE) and carbonic anhydrases ... -
LC-HRMS Profiling and Phenolic Content, Cholinesterase, and Antioxidant Activities of Terminalia citrina
Ebubekir Özler; Fevzi Topal; Meryem Topal; Sevim Beyza Öztürk Sarıkaya (WILEY, 2023)Terminalia citrina (T. citrina) belongs to the Combretaceae family and is included in the class of medicinal plants in tropical countries such as Bangladesh, Myanmar, and India. The antioxidant activities of lyophilized ...