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Comparison of Verona integron-borne metallo-ß-lactamase (VIM) variants reveals differences in stability and inhibition profiles
(2016-03)
Metallo-β-lactamases (MBLs) are of increasing clinical significance; the development of clinically useful MBL inhibitors is challenged by the rapid evolution of variant MBLs. The Verona integron-borne metallo-β-lactamase ...
Distribution of ß-lactamase genes among carbapenem-resistant Klebsiella pneumoniae strains isolated from patients in Turkey
(2015-11)
Background
The emergence of carbapenem-resistant Klebsiella pneumoniae poses a serious problem to antibiotic management. We investigated the β-lactamases in a group of carbapenem-resistant K. pneumoniae clinical isolates ...
Çoklu-İlaç Dirençli P. aeruginosa ve E. coli Suşlarında Antibiyotik Direnç Genlerinin ve Sınıf 1 İntegron Gen Kasetlerinin Araştırılması
(2018)
P. aeruginosa ve E.coli izolatlarının birçok antibiyotiğe direnç kazanması nedeniyle bu patojenlerin neden olduğu enfeksiyonların tedavisi zorlaşmıştır. Bundan dolayı klinik izolatlarda antibiyotik direnç genlerinin ...
Determination of a novel integron-located variant (blaOXA-320) of Class D ß-lactamase in Proteus mirabilis
(2014-10)
Proteus mirabilis (P. mirabilis) is one of Gram-negative pathogens encountered in clinical specimens. A clinical isolate (TRP41) of P. mirabilis was isolated from a Turkish patient in Turkey. The isolate was identified ...
Nationwide study of Escherichia coli producing extended-spectrum ß-lactamases TEM, SHV and CTX-M in Turkey
(2013-11)
Four hundred and forty extended-spectrum β-lactamase (ESBL)-producing Escherichia coli isolates were collected from 10 different hospitals in Turkey between 2011 and 2012. Clinical specimens consisted of urine (80.45%), ...