Ara
Toplam kayıt 52, listelenen: 31-40
An analytical approach based on ESI-MS, LC–MS and PCA for the quali–quantitative analysis of cycloartane derivatives in Astragalus spp.
(Journal of Pharmaceutical and Biomedical Analysis, 2013-07-08)
Astragalus species are widely used as health foods and dietary supplements, as well as drugs in traditional medicine. To rapidly evaluate metabolite similarities and differences among the EtOH extracts of the roots of eight ...
Synthesis, structural characterization of Co(II), Ni(II) and Cu(II) complexes of azo dye ligands derived from dihydroxynaphthalene
(2014-10-21)
[Abstract Not Available]
Comparison of Verona integron-borne metallo-ß-lactamase (VIM) variants reveals differences in stability and inhibition profiles
(2016-03)
Metallo-β-lactamases (MBLs) are of increasing clinical significance; the development of clinically useful MBL inhibitors is challenged by the rapid evolution of variant MBLs. The Verona integron-borne metallo-β-lactamase ...
Characterization of novel VIM carbapenemase, VIM-38, and first detection of GES-5 carbapenem-hydrolyzing ß-lactamases in Pseudomonas aeruginosa in Turkey
(2014-03)
Pseudomonas aeruginosa isolates were collected form a Turkish hospital. Antimicrobial susceptibility was performed using the Vitek 2 Compact system, and 24 isolates were categorized as multidrug resistant (n = 18), ...
Effect of amino acid substitution in New Delhi metallo-ß-lactamase on carbapenem susceptibility
(2018-04)
The aim of this work was investigation of clinically important amino acid substitutions of NDM-1 variants. A blaNDM-1 gene was cloned into expression vector pET100/D-TOPO. The sequence of NDM-1 variants with substituted ...
Distribution of ß-lactamase genes among carbapenem-resistant Klebsiella pneumoniae strains isolated from patients in Turkey
(2015-11)
Background
The emergence of carbapenem-resistant Klebsiella pneumoniae poses a serious problem to antibiotic management. We investigated the β-lactamases in a group of carbapenem-resistant K. pneumoniae clinical isolates ...
Çoklu-İlaç Dirençli P. aeruginosa ve E. coli Suşlarında Antibiyotik Direnç Genlerinin ve Sınıf 1 İntegron Gen Kasetlerinin Araştırılması
(2018)
P. aeruginosa ve E.coli izolatlarının birçok antibiyotiğe direnç kazanması nedeniyle bu patojenlerin neden olduğu enfeksiyonların tedavisi zorlaşmıştır. Bundan dolayı klinik izolatlarda antibiyotik direnç genlerinin ...
Determination of a novel integron-located variant (blaOXA-320) of Class D ß-lactamase in Proteus mirabilis
(2014-10)
Proteus mirabilis (P. mirabilis) is one of Gram-negative pathogens encountered in clinical specimens. A clinical isolate (TRP41) of P. mirabilis was isolated from a Turkish patient in Turkey. The isolate was identified ...
Esansiyel Hipertansiyonlu Hastalarda M235T Anjiotensinojen Gen Polimorfizmi
(Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi, 2016-04)
Esansiyel hipertansiyon, patogenezinde çeşitli
genlerin rol oynadığı poligenik bir hastalıktır. Kan
basıncının regülasyonunda görev yapan renin angiotensin sistemi (RAS) aynı zamanda
hipertansiyon gelişimine de neden ...
Kinetic characterization of GES-22 ß-lactamase harboring the M169L clinical mutation
(2016-12)
The class A β-lactamase GES-22 has been identified in Acinetobacter baumannii isolates in Turkey, and subsequently shown to differ from GES-11 by a single substitution (M169L). Because M169 is part of the omega loop, a ...