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Comparison of Verona integron-borne metallo-ß-lactamase (VIM) variants reveals differences in stability and inhibition profiles
(2016-03)
Metallo-β-lactamases (MBLs) are of increasing clinical significance; the development of clinically useful MBL inhibitors is challenged by the rapid evolution of variant MBLs. The Verona integron-borne metallo-β-lactamase ...
Distribution of ß-lactamase genes among carbapenem-resistant Klebsiella pneumoniae strains isolated from patients in Turkey
(2015-11)
Background
The emergence of carbapenem-resistant Klebsiella pneumoniae poses a serious problem to antibiotic management. We investigated the β-lactamases in a group of carbapenem-resistant K. pneumoniae clinical isolates ...
Determination of a novel integron-located variant (blaOXA-320) of Class D ß-lactamase in Proteus mirabilis
(2014-10)
Proteus mirabilis (P. mirabilis) is one of Gram-negative pathogens encountered in clinical specimens. A clinical isolate (TRP41) of P. mirabilis was isolated from a Turkish patient in Turkey. The isolate was identified ...
Nationwide study of Escherichia coli producing extended-spectrum ß-lactamases TEM, SHV and CTX-M in Turkey
(2013-11)
Four hundred and forty extended-spectrum β-lactamase (ESBL)-producing Escherichia coli isolates were collected from 10 different hospitals in Turkey between 2011 and 2012. Clinical specimens consisted of urine (80.45%), ...