Ara
Toplam kayıt 8, listelenen: 1-8
Comparison of Verona integron-borne metallo-ß-lactamase (VIM) variants reveals differences in stability and inhibition profiles
(2016-03)
Metallo-β-lactamases (MBLs) are of increasing clinical significance; the development of clinically useful MBL inhibitors is challenged by the rapid evolution of variant MBLs. The Verona integron-borne metallo-β-lactamase ...
Characterization of novel VIM carbapenemase, VIM-38, and first detection of GES-5 carbapenem-hydrolyzing ß-lactamases in Pseudomonas aeruginosa in Turkey
(2014-03)
Pseudomonas aeruginosa isolates were collected form a Turkish hospital. Antimicrobial susceptibility was performed using the Vitek 2 Compact system, and 24 isolates were categorized as multidrug resistant (n = 18), ...
Distribution of ß-lactamase genes among carbapenem-resistant Klebsiella pneumoniae strains isolated from patients in Turkey
(2015-11)
Background
The emergence of carbapenem-resistant Klebsiella pneumoniae poses a serious problem to antibiotic management. We investigated the β-lactamases in a group of carbapenem-resistant K. pneumoniae clinical isolates ...
Determination of a novel integron-located variant (blaOXA-320) of Class D ß-lactamase in Proteus mirabilis
(2014-10)
Proteus mirabilis (P. mirabilis) is one of Gram-negative pathogens encountered in clinical specimens. A clinical isolate (TRP41) of P. mirabilis was isolated from a Turkish patient in Turkey. The isolate was identified ...
Kinetic characterization of GES-22 ß-lactamase harboring the M169L clinical mutation
(2016-12)
The class A β-lactamase GES-22 has been identified in Acinetobacter baumannii isolates in Turkey, and subsequently shown to differ from GES-11 by a single substitution (M169L). Because M169 is part of the omega loop, a ...
A Novel Integron Gene Cassette Harboring VIM-38 Metallo-ß-lactamase in a Clinical Pseudomonas aeruginosa Isolate
(2016-11)
[Abstract Not Available]
OXA- and GES-type ß-lactamases predominate in extensively drug-resistant Acinetobacter baumannii isolates from a Turkish University Hospital
(2014-05-01)
We determined the antibiotic susceptibility and genetic mechanisms of resistance in clinical strains of Acinetobacter baumannii from Istanbul, Turkey. A total of 101 clinical strains were collected between November 2011 ...
Screening of Class 1 and Class 2 integrons in clinical isolates of Pseudomonas aeruginosa collected from seven hospitals in Turkey: A multicenter study
(2013-12)
Pseudomonas aeruginosa is one of the leading nosocomial pathogens worldwide, and their infections are difficult to treat due to acquired resistance to many antibiotics. This study aimed to detect class 1 and 2 integrons ...