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Distribution of beta-Lactamase Genes Among Carbapenem-Resistant Klebsiella pneumoniae Strains Isolated From Patients in Turkey
(Korean Soc Laboratory Medicine, 2015)
Background: The emergence of carbapenem-resistant Klebsiella pneumoniae poses a serious problem to antibiotic management. We investigated the beta-lactamases in a group of carbapenem-resistant K. pneumoniae clinical isolates ...
BIOLOGICAL ACTIVITIES AND PHYTOCHEMICAL SCREENING OF ETHANOL EXTRACTS FROM ADONIS PARYADRICA (RANUNCULACEAE)
(Soc Stiinte Farmaceutice Romania, 2020)
In this study, secondary metabolite profiles of flower, leaf and root of Adonis paryadrica ethanolic extracts were performed by using a newly developed and validated LC-MS/MS method. For this purpose, the LC-MS/MS system ...
Determination of antibiotic resistance genes and virulence factors in Escherichia coli isolated from Turkish patients with urinary tract infection
(Soc Brasileira Medicina Tropical, 2019)
Introduction: Escherichia coli ranks among the most common sources of urinary tract infections (UTI). Methods: Between November 2015 and August 2016, 90 isolates of E coli were isolated from patients at Rize Education and ...
EFFECT OF AMINO ACID SUBSTITUTION IN NEW DELHI METALLO-beta-LACTAMASE ON CARBAPENEM SUSCEPTIBILITY
(Akademiai Kiado Zrt, 2018)
The aim of this work was investigation of clinically important amino acid substitutions of NDM-1 variants. A bla(NDM-1) gene was cloned into expression vector pET100/D-TOPO. The sequence of NDM-1 variants with substituted ...
NEXT-GENERATION SEQUENCING OF PLASMID CARRYING bla(OXA-48) IN KLEBSIELLA PNEUMONIAE FROM TURKEY
(Akademiai Kiado Zrt, 2019)
A carbapenem-resistant Klebsiella pneumoniae strain was isolated in Turkey in 2012 and bla(NDM-1) and bla(OXA-48) genes were observed in this strain. The aim of this study was to investigate transferability of plasmid ...
Kinetic characterization of GES-22 beta-lactamase harboring the M169L clinical mutation
(Japan Antibiotics Research Assoc, 2016)
The class A p-lactamase GES-22 has been identified in Acinetobacter baumannii isolates in Turkey, and subsequently shown to differ from GES-11 by a single substitution (M169L). Because M169 is part of the omega loop, a ...