| dc.contributor.author | Iraz, Meryem | |
| dc.contributor.author | Özad Düzgün, Azer | |
| dc.contributor.author | Çopur Çiçek, Ayşegül | |
| dc.contributor.author | Bonnin, Remy A. | |
| dc.contributor.author | Ceylan, Ayşenur | |
| dc.contributor.author | Saral, Ayşegül | |
| dc.contributor.author | Nordmann, Patrice | |
| dc.contributor.author | Sandallı, Cemal | |
| dc.date.accessioned | 2019-12-18T11:01:43Z | |
| dc.date.available | 2019-12-18T11:01:43Z | |
| dc.date.issued | 2014-03 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12440/1766 | |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0732889313006457 | |
| dc.description.abstract | Pseudomonas aeruginosa isolates were collected form a Turkish hospital. Antimicrobial susceptibility was performed using the Vitek 2 Compact system, and 24 isolates were categorized as multidrug resistant (n = 18), extensively-drug resistant (n = 5), or pan-drug resistant (n = 1). PCR and DNA sequence analysis revealed that 1 strain possessed the blaGES-5 and another carried a novel blaVIM variant, named VIM-38. This new gene exhibited 1 amino acid substitution (Ala265Val) in comparison to its closest variant, VIM-5. Both VIM encoding genes were clones and demonstrated similar susceptibility profile when expressed in identical background. The presence of VIM-38 increases the diversity of carbapenemases in Turkey | en_US |
| dc.language.iso | eng | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | [No Keywords] | en_US |
| dc.title | Characterization of novel VIM carbapenemase, VIM-38, and first detection of GES-5 carbapenem-hydrolyzing ß-lactamases in Pseudomonas aeruginosa in Turkey | en_US |
| dc.type | article | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.department | Fakülteler, Mühendislik ve Doğa Bilimleri Fakültesi, Genetik ve Biyomühendislik Bölümü | en_US |
| dc.contributor.institutionauthor | Özad Düzgün, Azer | |
