Gümüşhane Sağlık Hizmetleri Meslek Yüksekokulu
https://hdl.handle.net/20.500.12440/71
2024-03-28T16:23:36Z
2024-03-28T16:23:36Z
Two new species of Phalangium (Opiliones: Phalangiidae) from Turkey
Kurt, Kemal
Erdek, Melek
Kurt, Pinar
https://hdl.handle.net/20.500.12440/6086
2023-11-16T08:27:19Z
2023-01-01T00:00:00Z
Two new species of Phalangium (Opiliones: Phalangiidae) from Turkey
Kurt, Kemal; Erdek, Melek; Kurt, Pinar
Two new harvestmen species, Phalangium nalanae sp. n. and Phalangium taylani sp. n., are described, diagnosed and illustrated based on male material from Hakkari Province, Turkey. Also, the differences between two new species and similar species of the genus Phalangium are discussed. © 2023 Magnolia Press.
2023-01-01T00:00:00Z
Determination of the Antioxidant Capacity of Puerarin and Its Effect on Cholinesterases by in vitro and in silico Methods
İnan Ergün, Aslı
Topal, Meryem
https://hdl.handle.net/20.500.12440/6085
2023-11-16T07:44:31Z
2023-01-01T00:00:00Z
Determination of the Antioxidant Capacity of Puerarin and Its Effect on Cholinesterases by in vitro and in silico Methods
İnan Ergün, Aslı; Topal, Meryem
Puerarin, which was used as a natural isoflavone in this study, was obtained from the Kudzu plant. The inhibitory effect of puerarin on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes was investigated. The IC50 values of AChE (177.73 nM) and BChE (315.07 nM) were determined. The binding mechanism of puerarin, which has a high inhibitory effect on the active site of the enzyme, was demonstrated by the molecular docking method. The antioxidant activity was evaluated for the same molecule. For this purpose, Fe3+-Fe2+ reducing capacity, ABTS radical scavenging activity, CUPRAC method, DPPH⋅ scavenging activity and DMPD radical scavenging method were used. The percentage (%) inhibition amount of puerarin molecule was calculated as 99.33 % for ABTS radical scavenging activity, which is the more preferred method for natural products. The absorbtion value of iron reduction of Puerarin was 0.122±0.010, and the value of copper reduction was 0.633±0.026. Our research efforts include uncovering the potent antioxidant potential of puerarin and, simultaneously, a comparative study of tacrine, primarily emphasizing its inhibitory effects against AChE and BChE enzymes. The puerarin is expected to be a guide for drug discovery against many problems, especially oxidative cell damage in Alzheimer's disease, mitochondrial dysfunction (MD), cancer, and cardiovascular diseases. © 2023 Wiley-VCH GmbH.
2023-01-01T00:00:00Z
A barrier to participation in cervical cancer screenings: fatalism
Duru, Gökçem
Topatan, Serap
https://hdl.handle.net/20.500.12440/5961
2023-06-13T12:30:02Z
2023-01-01T00:00:00Z
A barrier to participation in cervical cancer screenings: fatalism
Duru, Gökçem; Topatan, Serap
Cervical cancer is a significant disease affecting women's health in terms of its incidence and is one of the most preventable cancers. However, participation in early cervical cancer-screening programs has been unsatisfactory for various reasons. In this descriptive, relationship-seeking study, we examined the relationship between fatalism tendency, an individual barrier to participation in early cancer screening programs, and women's attitudes toward the early diagnosis of cervical cancer and undergoing the Pap smear test. Research data were collected between August 1, 2019 and December 1, 2019, in a city in northern Turkey from 602 women using a participant information form, the Attitudes Toward Early Diagnosis in Cervical Cancer Scale, and the Fatalism Tendency Scale. We found that fatalistic tendencies in women were a predictor of their attitudes toward the early diagnosis of cervical cancer (odds ratio [OR] = -0.64, β = .47, p < .001) and undergoing the Pap smear test (OR = 1.01, β = -.15, p < .001). Women with high fatalism tendencies had a more negative attitude toward the early diagnosis of cervical cancer and their participation rate in Pap smear screening programs was low. Therefore, nurses must consider women's fatalistic tendencies and attitudes toward cancer when organizing educational and informational programs that encourage participation in cervical cancer screening.
2023-01-01T00:00:00Z
DESCRIPTION OF THE UNKNOWN FEMALE OF THE HARVESTMAN RAFALSKIA AZIZSANCARI KURT, YAGMUR & TEZCAN, 2019 (ARACHNIDA: OPILIONES: PHALANGIIDAE) FROM TURKEY
Kurt, Kemal
Yagmur, Ersen Aydin
Kurt, Pinar
https://hdl.handle.net/20.500.12440/5957
2023-06-08T12:26:36Z
2023-01-01T00:00:00Z
DESCRIPTION OF THE UNKNOWN FEMALE OF THE HARVESTMAN RAFALSKIA AZIZSANCARI KURT, YAGMUR & TEZCAN, 2019 (ARACHNIDA: OPILIONES: PHALANGIIDAE) FROM TURKEY
Kurt, Kemal; Yagmur, Ersen Aydin; Kurt, Pinar
The female of Rafalskia azizsancari Kurt, Yagmur & Tezcan, 2019, previously known only from the male in Turkey, is now described based on new material from Odemis District, Izmir Province, Turkey. Detailed morphological descriptions, photographs and illustration of the female ovipositor are provided.Keywords
2023-01-01T00:00:00Z